What it does is gently reduce the chemical “reinforcement” that substances like alcohol or opioids create. When someone drinks or uses opioids while on Naltrexone, the expected effect — the reward — often doesn’t arrive. Because without the usual payoff, the ritual begins to unravel. It tells you something about timing, triggers, or support systems.
Naltrexone has shown consistent effectiveness in reducing alcohol consumption and relapse rates, making it a valuable tool for alcohol addiction treatment. Naltrexone is an opioid antagonist medication used to treat alcohol dependence and opioid use disorder. It works by blocking opioid receptors in the brain, reducing cravings and the pleasurable effects of alcohol and opioids. Unlike opioids, it is non-addictive and does not produce euphoric effects.
Does naltrexone help with alcohol cravings?
If you’re a treatment provider and have a question, please reach out and someone from our Customer Success team will be in touch with you shortly. A study “Naltrexone Treatment for Pregnant Women With Opioid Use Disorder” by Elisha M Wachman, et al. 2019, reported that 83% of women on naltrexone breastfed without immediate issues in the perinatal period. Naltrexone has been detected in breast milk in a single case study, with the infant receiving less than 1% of the maternal dose. However, further research is necessary to make definitive recommendations about its safety during breastfeeding. Olympic Behavioral Health is an approved provider for Blue Shield and Tufts, while also accepting many other major insurance carriers. Olympic Behavioral Health is an approved provider for Blue Shield and Tufts while also accepting many other major insurance carriers.
Related Disease Conditions
Naltrexone is a medication approved by the Food and Drug Administration (FDA) and used marijuana addiction in medication-assisted treatment (MAT) to treat both opioid and alcohol use disorders. By targeting the biological and psychological components of addiction, naltrexone strengthens recovery outcomes during addiction treatment across both substance categories. The prescription opioid antagonist, called naltrexone, was first approved by the FDA to treat opioid dependence in 1984.

Do You Need A Prescription For Naltrexone in Florida?
Opioid use disorder can affect every aspect of your life, from your home life and personal relationships, mental and physical health, to your professional endeavors and finances. Opioid use disorder can result in unintentional overdose, which can be deadly. Naltrexone also works on part of the brain known as the hypothalamic pituitary axis (HPA), which plays a key role in the body’s stress response, which can be dysregulated in the presence of alcohol. It is still unclear exactly how it works on the HPA to treat alcohol use disorder. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Autoimmune Disorders

It also may block the euphoric and rewarding feeling that may make you want naltrexone side effects to use alcohol. It will not produce any opioid-like effects or cause mental or physical dependence. It will not prevent you from becoming impaired while drinking alcohol or using opioids. Perhaps the most evidence to date for off-label use of low-dose naltrexone is fibromyalgia, as noted by Dr. Manasa Irwin in a recent AFP letter to the editor.
Ultra Rapid Opioid Withdrawal
Let your healthcare provider know if you or anyone in your family has tried to commit suicide. No, you should not take naltrexone while pregnant or breastfeeding unless prescribed by a doctor, as research on its safety is limited. Naltrexone crosses the placenta and is present in breast milk.
Contraindications for Naltrexone Treatment
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. If you’ve just picked up your prescription and you’re staring at the bottle wondering, “Am I doing this right? Starting a new medication, especially one tied to recovery, can stir a mix of caution and pressure. What matters most isn’t whether the medication works — but whether it’s working in the right moment, with the right support.
- For individuals considering Naltrexone for any medical use, consulting with a healthcare provider is essential for personalized advice based on the latest research and individual health considerations.
- Any attempt by a patient to overcome the antagonism by taking opioids is especially dangerousand may lead to life-threatening opioid intoxication or fatal overdose.
- By mitigating cravings and the pleasurable effects of these substances, naltrexone supports individuals in their recovery efforts.
- This reaction, called precipitated withdrawal, includes vomiting, pain, and agitation.
Ask your doctor or pharmacist any questions you have about naltrexone. Call your doctor if you have any unusual problems while taking this medication. Alcohol Use Disorder (AUD) affects millions worldwide, causing significant health, social, and economic burdens.

Effectiveness in Opioid Dependence Treatment
In alcohol use disorder, naltrexone has been shown to significantly reduce cravings and drinking frequency, especially when combined with behavioral interventions. The recommended dosage of naltrexone is 50 mg per day for alcohol use disorder and opioid use disorder when taken as an oral tablet. The extended-release injection is administered at 380 mg once per month as an intramuscular shot by a healthcare provider. Dosage adjustments are needed https://www.sadurska.com/the-hidden-cause-of-your-brain-fog-3/ for individuals with liver impairment, requiring close monitoring to prevent adverse effects.